Preparations with oxandrolone do not cause much damage to the liver, in spite of the fact that it is a 17-alpha-acallated steroid. According to the studies, the use of Anavar in a daily dosage of 20 milligrams does not affect the state of liver enzymes. Oxandrolone does not aromatize, and therefore does not cause estrogenic manifestations. Possible side effects from Oxandrolone are related to the ability of the steroid to inhibit the production of its own testosterone, albeit insignificantly. If the recommended dosages are exceeded, the endogenous level of the hormone is regarded by the body as too high, and it ceases to secrete testosterone. In the most severe cases, this can result in testicular atrophy. But if you comply with the rules that contain instructions for the use of Anavar, and follow the recommendations of the doctor, then negative reactions in 99% of cases do not arise.